Methionine Therapy for autoimmune disorders

When one has any type of autoimmune disorder it is important to see if the autoimmune problem is actually being caused by a deficiency whereby the body is harvesting (from itself) the thing it is lacking. The most common is Methionine. It is an amino acid needed in every single cell cycle of the body, and is required to build or heal nearly everything.

Methionine must always be taken with a high level B-complex because the Bs are necessary for one's body to use the methionine. If one is not supplementing with a high level of B-complex then B deficiency will occur, which has nasty side effects.

The first step is to make sure one is able to uptake the B-vitamins. Any B-complex will do, however it is best if it is a 'time release' or 'sustained release' B complex as Bs are water soluble and so are instantly released into your urine if you do not need them right then. Select a B-complex, and take a full 'daily dose' every 12 hours. Your urine should be a neon yellow-green color. If it is NOT, then you are incredibly B-complex deficient, and you will need to purchase 'Intrinsic Factor' the name might also have the word 'B' in it.

You can buy these things from Amazon, or www.vitacost.com or any other online place that you prefer.

After you have succeeded in having neon urine, then you may begin taking methionine with your B-complex (and Intrinsic Factor if needed). The ONLY brand of methionine you should take is Country Life Methionine. There is only one dosage. Country Life is the only one that is pure enough to take at a therapeutic level. 

Every 12 hours you take a FULL dose of your B-complex (read the label to make sure what a full daily dose is), along with 2 methionine. If you needed the Intrinsic Factor then include the IF for 6 weeks, and then stop JUST the IF and see if your urine is still neon, if so, then you stop the IF until/unless your urine stops being neon.

The full dose of methionine is FOUR methionine, and double the daily dose of B-complex. Stay on the full dose for 3 months to see if your symptoms diminish over time. It is a gradual process as your body begins to heal itself, so do not expect that *suddenly* you will be magically better. Pay attention to your pain level every day, and note which symptoms are bothering you. As a species our brain wants to forget how uncomfortable we were, so often times people will be on the methionine for a few months and then decide it isn't working for them even though their symptoms have stopped. But about a month after they stop the methionine their symptoms return because their body was not finished healing, and is still in deficit.

Some people can switch to a 1/2 dose (2 methionine and a single dose of B-complex every 24 hours) after a few months, and after a year or so, stop taking it all together until they start having symptoms again. Other people can never stop taking it. If the methionine is the issue in your system, then you will need to experiment on yourself and see what is  best for you in the long term.

If you have been on high blood pressure medication, or cholesterol medication, methionine might correct the issue, and suddenly you could be on medication that you do not need. This can be dangerous. If you are on high blood pressure/cholesterol medication, please check your blood pressure every single day, and your cholesterol every 6 weeks. So that your meds may be adjusted accordingly.

If you have been on pain medication or muscle relaxers for your symptoms, and you stop taking them, you are likely to have withdrawal symptoms. Those symptoms are NOT a side-effect of the methionine nor of the B-complex.

If you have been having difficulty getting pregnant, being on the methionine therapy is likely to help. If you become pregnant from taking the methionine therapy the you should NOT STOP TAKING THE METHIONINE AND B COMPLEX during your pregnancy. The methionine has allowed your body to stop feeling as if you are not healthy enough to support a fetus. If you stop taking it your body will revert to a state where it feels it is not able to support a fetus, and you are likely to miscarry. The methionine and B-complex will not negatively impact your baby.

stuff about methionine

Symptoms: (someone could have any or all of these symptoms, to any
degree and in any combo, and various progressions)
Vertigo
Feeling like their eyes flick back and forth (left/right) when trying
to stare at an object directly for more than a second or two)
Feeling like their eyes are 'vibrating' or 'buzzing', and easily get
eye strain
Unusually low, or exceedingly high BP
High Cholesterol
Yeast/Candida issues of any kind (skin, vaginal, digestive tract, etc)
Allergies of any kind
Hypersensitive to environment (strong lights, certain sounds, strong
smells)(becomes easily allergic to new things)
Food allergies
Asthma, especially with a throat tickle
Bad taste in mouth even that returns shortly after brushing teeth
Sensitive skin, easy to rash, might have a history of eczema, or
psoriasis, but not necessary. Rash can look raspberry, and/or have
small little blisters (singly or in clusters), or look like 'mosquito
bites', or just be red and itch in that good/bad way that mosquito
bites do, or feel like a burning/pricking sensation.
Sensation of bug crawling on certain areas of the body, scratching
makes it stop for about 30-60 seconds, but then returns.
Scalp itches/crawls/tickles
Muscles 'burn' when walking even a short distance (due to anaerobic
consumption of lactose, instead of aerobic first)(potassium helps)
Over time, burn can become more acute and become knots and then spasms
Trouble sleeping. Usually manifests as either not being able to fall
asleep, or falls asleep but then sleeps fitfully. I have seen full-
blown insomnia occur in some people
Digestive problems that often appear to be IBS, spastic bowel, as
well as painful gas, smelly gas, delayed bowel movements, the
sensation of constipation even when stools are very soft (you push
but it won't come out), hurts stomach to eat, no desire to eat even
when hungry, acid reflux, indigestion, food doesn't taste good.
Dry mouth
Dry nasal passages, even when nose runs it feels like the skin inside
is cracking
Extremely dry feeling skin, even when it is oily/waxy.
Tight/itchy skin
Counter-intuitive reactions to medications (take a pain med and have
headache get worse)
Changes in sex drive/libido/menstrual/trouble getting pregnant/bad
cramps/bad PMS
Sensitive to hormones like BCP
If taking antihistamines improves allergies, but makes other symptoms
worse.
If most antihistamines don't work at all.
Sensitive to the sun (can cause rashes, or blisters (not meaning burn
blisters, other kinds of blisters)
Eyes sensitve to light, and difficulty sleeping if not in a totally
pitch-black room
Oddly: if when you go outside you have a penchance to close one eye
in response to brightness or plug one ear in response to noise
Difficulty regulating own body temperature, tends towards over-
heating, or always too cold, gets dizzy with heat
People can be voracious eaters that can't keep their weight on, or
have Cushing's Syndrome type fat distribution and nothing they do
seems to allow them to lose it, or they might not have any weight
issues at all.

If someone appears to have symptoms of Cushing's Syndrome, but does
not actually have high cortisol levels, that would make them 90% or
more likely to be methionine deficient, in my experience. There are
questionnaires online (that are pages and pages long) to help
determine if someone might have CS. I would recommend looking at
some of those.

Symptoms similar to Wilson's can also mean someone is methionine
deficient.

Restless leg syndrome my be related, but unsure
Fibromyalgia might be related too, but also unsure

Questions I ask:
What foods do you crave? (If they say 'none' don't believe them...
ask them to take a week, and before they eat, when they are hungry,
have them imagine what foods they would eat if they could have
anything magically appear in front of them. Most people do not pay
any attention to their cravings, and so are unaware they are even
having them) If people have a specific set of foods that they crave
over and over, then it usually is pretty easy to tell what they are
likely to be deficient in. Here are some example: broccoli, meat,
chocolate combos are usually iron. Potatoes and cheese is likely
lysine. cheese, eggs, dairy, meat: methionine. meat, beans, cheese:
protein I think you get the drift.

Are there any times of the day that your symptoms are worse?

Has your sex-drive changed since your other symptoms began? As your
menstrual changes since your other symptoms began?

What is your sleep like? What is the longest you can normally sleep?

* If someone starts on the methionine and begins to crave milk more
strongly, that is something we need to look into. They might be
becoming glycine deficient. I have only just started looking at
this. Apparently consuming excess methionine can put a demand on
glycine for other metabolic processes. More research will need to be
done in this area.

* Some people become Lysine deficient, or are also lysine deficient,
and those symptoms look like: raised urea content (doesn't have to be
high enough for gout, but if they have gout, they are lysine
deficient), achy joints in general, (instead of muscles, which is L-
meth deficiency), cold-sore, or really any kind of mouth sores, some
inability to think clearly, sore throat/cough and or fighting off
colds or feeling like they have worse allergies, even if it isn't
allergy season. Also can have memory and concentration issues. When
people are lysine deficient they have too much Arginine in their
system which leads to higher urea content in their blood, and Arg
allows viruses to have an easier time reproducing (which puts a
stronger strain on the immune system). Also, the brain needs
Arginine bound to Lysine to help repair the brain, and when lysine
deficient that doesn't happen, so cognitive abilities decline, and
can get worse over time, effecting short term memory, and short to
long memory writing.

I think that is a good starting point:) Please let me know if you
have any questions about what I have said, or why. I haven't had a
chance to go look through papers again, but I can still do that if
you want me to (just not right this second) :)

Please ask me if there are any symptoms I didn't put here, but that
you want to know if I feel they are methionine related. I am sure I
didn't list everything, there are just so many symptoms and I am sure
I have forgotten many. If you send me a list of symptoms I can tell
you what I think they are related to, and why, if I know why (or
think I know why).