Sunday, April 13, 2008

stuff about methionine

Symptoms: (someone could have any or all of these symptoms, to any
degree and in any combo, and various progressions)
Vertigo
Feeling like their eyes flick back and forth (left/right) when trying
to stare at an object directly for more than a second or two)
Feeling like their eyes are 'vibrating' or 'buzzing', and easily get
eye strain
Unusually low, or exceedingly high BP
High Cholesterol
Yeast/Candida issues of any kind (skin, vaginal, digestive tract, etc)
Allergies of any kind
Hypersensitive to environment (strong lights, certain sounds, strong
smells)(becomes easily allergic to new things)
Food allergies
Asthma, especially with a throat tickle
Bad taste in mouth even that returns shortly after brushing teeth
Sensitive skin, easy to rash, might have a history of eczema, or
psoriasis, but not necessary. Rash can look raspberry, and/or have
small little blisters (singly or in clusters), or look like 'mosquito
bites', or just be red and itch in that good/bad way that mosquito
bites do, or feel like a burning/pricking sensation.
Sensation of bug crawling on certain areas of the body, scratching
makes it stop for about 30-60 seconds, but then returns.
Scalp itches/crawls/tickles
Muscles 'burn' when walking even a short distance (due to anaerobic
consumption of lactose, instead of aerobic first)(potassium helps)
Over time, burn can become more acute and become knots and then spasms
Trouble sleeping. Usually manifests as either not being able to fall
asleep, or falls asleep but then sleeps fitfully. I have seen full-
blown insomnia occur in some people
Digestive problems that often appear to be IBS, spastic bowel, as
well as painful gas, smelly gas, delayed bowel movements, the
sensation of constipation even when stools are very soft (you push
but it won't come out), hurts stomach to eat, no desire to eat even
when hungry, acid reflux, indigestion, food doesn't taste good.
Dry mouth
Dry nasal passages, even when nose runs it feels like the skin inside
is cracking
Extremely dry feeling skin, even when it is oily/waxy.
Tight/itchy skin
Counter-intuitive reactions to medications (take a pain med and have
headache get worse)
Changes in sex drive/libido/menstrual/trouble getting pregnant/bad
cramps/bad PMS
Sensitive to hormones like BCP
If taking antihistamines improves allergies, but makes other symptoms
worse.
If most antihistamines don't work at all.
Sensitive to the sun (can cause rashes, or blisters (not meaning burn
blisters, other kinds of blisters)
Eyes sensitve to light, and difficulty sleeping if not in a totally
pitch-black room
Oddly: if when you go outside you have a penchance to close one eye
in response to brightness or plug one ear in response to noise
Difficulty regulating own body temperature, tends towards over-
heating, or always too cold, gets dizzy with heat
People can be voracious eaters that can't keep their weight on, or
have Cushing's Syndrome type fat distribution and nothing they do
seems to allow them to lose it, or they might not have any weight
issues at all.

If someone appears to have symptoms of Cushing's Syndrome, but does
not actually have high cortisol levels, that would make them 90% or
more likely to be methionine deficient, in my experience. There are
questionnaires online (that are pages and pages long) to help
determine if someone might have CS. I would recommend looking at
some of those.

Symptoms similar to Wilson's can also mean someone is methionine
deficient.

Restless leg syndrome my be related, but unsure
Fibromyalgia might be related too, but also unsure


Questions I ask:
What foods do you crave? (If they say 'none' don't believe them...
ask them to take a week, and before they eat, when they are hungry,
have them imagine what foods they would eat if they could have
anything magically appear in front of them. Most people do not pay
any attention to their cravings, and so are unaware they are even
having them) If people have a specific set of foods that they crave
over and over, then it usually is pretty easy to tell what they are
likely to be deficient in. Here are some example: broccoli, meat,
chocolate combos are usually iron. Potatoes and cheese is likely
lysine. cheese, eggs, dairy, meat: methionine. meat, beans, cheese:
protein I think you get the drift.

Are there any times of the day that your symptoms are worse?

Has your sex-drive changed since your other symptoms began? As your
menstrual changes since your other symptoms began?

What is your sleep like? What is the longest you can normally sleep?


* If someone starts on the methionine and begins to crave milk more
strongly, that is something we need to look into. They might be
becoming glycine deficient. I have only just started looking at
this. Apparently consuming excess methionine can put a demand on
glycine for other metabolic processes. More research will need to be
done in this area.

* Some people become Lysine deficient, or are also lysine deficient,
and those symptoms look like: raised urea content (doesn't have to be
high enough for gout, but if they have gout, they are lysine
deficient), achy joints in general, (instead of muscles, which is L-
meth deficiency), cold-sore, or really any kind of mouth sores, some
inability to think clearly, sore throat/cough and or fighting off
colds or feeling like they have worse allergies, even if it isn't
allergy season. Also can have memory and concentration issues. When
people are lysine deficient they have too much Arginine in their
system which leads to higher urea content in their blood, and Arg
allows viruses to have an easier time reproducing (which puts a
stronger strain on the immune system). Also, the brain needs
Arginine bound to Lysine to help repair the brain, and when lysine
deficient that doesn't happen, so cognitive abilities decline, and
can get worse over time, effecting short term memory, and short to
long memory writing.

I think that is a good starting point:) Please let me know if you
have any questions about what I have said, or why. I haven't had a
chance to go look through papers again, but I can still do that if
you want me to (just not right this second) :)

Please ask me if there are any symptoms I didn't put here, but that
you want to know if I feel they are methionine related. I am sure I
didn't list everything, there are just so many symptoms and I am sure
I have forgotten many. If you send me a list of symptoms I can tell
you what I think they are related to, and why, if I know why (or
think I know why).

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